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ARFIP2 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P53365 |
| Other Accession | NM_012402, NP_036534 |
| Reactivity | Human, Mouse, Rat, Pig, Sheep, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Pig, Sheep, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 38kDa |
| Gene ID | 23647 |
|---|---|
| Alias Symbol | POR1 |
| Other Names | Arfaptin-2, ADP-ribosylation factor-interacting protein 2, Partner of RAC1, Protein POR1, ARFIP2, POR1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-ARFIP2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | ARFIP2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ARFIP2 {ECO:0000303|PubMed:30917996, ECO:0000312|HGNC:HGNC:17160} |
|---|---|
| Function | Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network (PubMed:26507660). May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2 (PubMed:26507660). Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site (PubMed:31204568, PubMed:30917996). Involved in phagophore growth during mitophagy by regulating ATG9A trafficking to mitochondria (PubMed:33773106). In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG (PubMed:26296658). |
| Cellular Location | Golgi apparatus. Golgi apparatus, trans-Golgi network membrane |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI10464
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