|Application ||WB, IHC|
|Other Accession||NM_001079862, NP_001073331|
|Reactivity||Human, Mouse, Rat, Bovine, Dog|
|Predicted||Human, Mouse, Pig, Guinea Pig|
|Alias Symbol||ACBD1, ACBP, CCK-RP, EP, MGC70414|
|Other Names||Acyl-CoA-binding protein, ACBP, Diazepam-binding inhibitor, DBI, Endozepine, EP, DBI|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-DBI antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||DBI antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.|
|Cellular Location||Endoplasmic reticulum. Golgi apparatus. Note=Golgi localization is dependent on ligand binding (PubMed:17953517)|
|Tissue Location||Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart.|
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Provided below are standard protocols that you may find useful for product applications.
Waga,C., (2007) Nihon Arukoru Yakubutsu Igakkai Zasshi 42 (6), 629-634 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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