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DBI antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P07108 |
| Other Accession | NM_001079862, NP_001073331 |
| Reactivity | Human, Mouse, Rat, Bovine, Dog |
| Predicted | Human, Mouse, Pig, Guinea Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 10kDa |
| Gene ID | 1622 |
|---|---|
| Alias Symbol | ACBD1, ACBP, CCK-RP, EP, MGC70414 |
| Other Names | Acyl-CoA-binding protein, ACBP, Diazepam-binding inhibitor, DBI, Endozepine, EP, DBI |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-DBI antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | DBI antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DBI |
|---|---|
| Function | Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. |
| Cellular Location | Endoplasmic reticulum. Golgi apparatus Note=Golgi localization is dependent on ligand binding (PubMed:17953517). |
| Tissue Location | Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Waga,C., (2007) Nihon Arukoru Yakubutsu Igakkai Zasshi 42 (6), 629-634 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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