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Tollip antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Tollip antibody - N-terminal region AI10484
    WB Suggested Anti-Tollip Antibody
    Titration: 1. μg/ml
    Positive Control: Mouse Brain
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9QZ06
Other Accession NM_023764, NP_076253
Reactivity Human, Mouse, Rat, Zebrafish, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Zebrafish, Pig, Chicken, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 30kDa
Additional Information
Gene ID 54473
Alias Symbol 4930403G24Rik, 4931428G15Rik
Other Names Toll-interacting protein, Tollip
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Tollip antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTollip antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tollip
Function Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity).
Cellular Location Cytoplasm.
Tissue Location Detected in heart, brain, spleen, lung, liver, skeletal muscle, kidney, thymus, pancreas and testis
Research Areas
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$ 293.00
Cat# AI10484
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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