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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   TBX6 antibody - N-terminal region   

TBX6 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - TBX6 antibody - N-terminal region AI10508
    WB Suggested Anti-TBX6 Antibody Titration: .2-1 μg/ml
    ELISA Titer: 1:625
    Positive Control: Human Placenta
  • IHC - TBX6 antibody - N-terminal region AI10508
    Human Muscle
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95947
Other Accession NM_004608, NP_004599
Reactivity Human, Mouse, Rat, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 47kDa
Additional Information
Gene ID 6911
Alias Symbol DFNB67
Other Names T-box transcription factor TBX6, T-box protein 6, TBX6
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-TBX6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTBX6 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBX6
Function T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through effects on Notch signaling around the node as well as through an effect on the morphology and motility of the nodal cilia (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00201}
Tissue Location Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus
Research Areas
Citations (0)

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Papapetrou,C., et al., (1999) Genomics 55 (2), 238-241Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:Leschik, J., Stefanovic, S., Brinon, B. & Pucéat, M. Cardiac commitment of primate embryonic stem cells. Nat. Protoc. 3, 1381-7 (2008). ICC/IF, Pig, Rat, Horse, Human, Mouse, Bovine, Dog, Guinea pig18772864Chen, Y.-L. et al. Smad6 inhibits the transcriptional activity of Tbx6 by mediating its degradation. J. Biol. Chem. 284, 23481-90 (2009). WB, Pig, Rat, Horse, Human, Mouse, Bovine, Dog, Guinea pig19561075

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$ 293.00
Cat# AI10508
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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