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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   TEAD4 antibody - middle region   

TEAD4 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - TEAD4 antibody - middle region AI10515
    WB Suggested Anti-TEAD4 Antibody Titration: .2-1 μg/ml
    ELISA Titer: 1:125
    Positive Control: Transfected 293T
  • IF - TEAD4 antibody - middle region AI10515
    Sample Type :

    Primary Antibody Dilution:

    4 μg/ml

    Secondary Antibody :

    Anti-rabbit Alexa 546

    Secondary Antibody Dilution:

    2 μg/ml

    Gene Name :

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15561
Other Accession NM_201441, NP_958849
Reactivity Human, Mouse, Rat, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Pig, Chicken, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 44kDa
Additional Information
Gene ID 7004
Alias Symbol EFTR-2, MGC9014, RTEF1, TCF13L1, TEF-3, TEFR-1, hRTEF-1B, TEF3
Other Names Transcriptional enhancer factor TEF-3, TEA domain family member 4, TEAD-4, Transcription factor 13-like 1, Transcription factor RTEF-1, TEAD4, RTEF1, TCF13L1, TEF3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-TEAD4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTEAD4 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TEAD4
Synonyms RTEF1, TCF13L1, TEF3
Function Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.
Cellular Location Nucleus.
Tissue Location Preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart
Research Areas
Citations (0)

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Appukuttan,B., (2007) Invest. Ophthalmol. Vis. Sci. 48 (8), 3775-3782 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:Chan, S. W. et al. TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. J. Biol. Chem. 284, 14347-58 (2009). WB, Pig, Human, Bovine, Dog, Horse, Rabbit, Guinea pig, Mouse, Rat19324876

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$ 293.00
Cat# AI10515
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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