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Tead4 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Tead4 antibody - middle region AI10516
    WB Suggested Anti-Tead4 Antibody
    Titration: 1. μg/ml
    Positive Control: Mouse Intestine
  • WB - Tead4 antibody - middle region AI10516
    WB Suggested Anti-Tead4 antibody Titration: 1 μg/ml

    Sample Type: Human heart
  • WB - Tead4 antibody - middle region AI10516
    WB Suggested Anti-Tead4 antibody Titration: 1 μg/ml

    Sample Type: Human liver
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q62296
Other Accession NM_011567, NP_035697
Reactivity Human, Mouse, Rat, Zebrafish, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Pig, Chicken, Bovine, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 48kDa
Additional Information
Gene ID 21679
Alias Symbol ETFR-2, Etfr2, FR-19, TEAD-4, TEF-3, Tcf13r1, Tef3, Tefr, Tefr1, Tefr1a
Other Names Transcriptional enhancer factor TEF-3, ETF-related factor 2, ETFR-2, TEA domain family member 4, TEAD-4, TEF-1-related factor 1, TEF-1-related factor FR-19, RTEF-1, Tead4, Tcf13r1, Tef3, Tefr1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Tead4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTead4 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tead4
Synonyms Tcf13r1, Tef3, Tefr1
Function Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif (By similarity). Might play a role in the embryonic development of skeletal muscle.
Cellular Location Nucleus.
Tissue Location Preferentially expressed in lung and in skeletal muscle
Research Areas
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$ 293.00
Cat# AI10516
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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