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TIPARP antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - TIPARP antibody - N-terminal region AI10558
    WB Suggested Anti-TIPARP Antibody Titration: .2-1 μg/ml
    ELISA Titer: 1:3125
    Positive Control: Human heart
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q7Z3E1
Other Accession NM_015508, NP_056323
Reactivity Human, Mouse, Rat, Pig, Horse, Bovine, Dog
Predicted Human, Rat, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 76kDa
Additional Information
Gene ID 25976
Alias Symbol DDF1, DKFZP434J214, DKFZp686N0351, DKFZp686P1838, FLJ40466, PARP-1, PARP-7, PARP7, pART14
Other Names TCDD-inducible poly [ADP-ribose] polymerase, 2.4.2.30, ADP-ribosyltransferase diphtheria toxin-like 14, ARTD14, Poly [ADP-ribose] polymerase 7, PARP-7, TIPARP, PARP7
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-TIPARP antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTIPARP antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TIPARP {ECO:0000303|PubMed:12851707, ECO:0000312|HGNC:HGNC:23696}
Function ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate, aspartate and cysteine residues on target proteins (PubMed:23275542, PubMed:25043379, PubMed:30373764). Acts as a negative regulator of AHR by mediating mono-ADP-ribosylation of AHR, leading to inhibit transcription activator activity of AHR (PubMed:23275542, PubMed:30373764).
Cellular Location Nucleus
Citations (0)
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References

Mehrle,A., Nucleic Acids Res. 34 (DATABASE ISSUE), D415-D418 (2006)Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:MacPherson, L. et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation. Nucleic Acids Res. 41, 1604-21 (2013). ICC/IF, IP, Human, Bovine, Dog, Horse, Pig, Rabbit, Rat, Mouse23275542

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$ 389.00
Cat# AI10558
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