TIPARP antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q7Z3E1 |
Other Accession | NM_015508, NP_056323 |
Reactivity | Human, Mouse, Rat, Pig, Horse, Bovine, Dog |
Predicted | Human, Rat, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 76kDa |
Gene ID | 25976 |
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Alias Symbol | DDF1, DKFZP434J214, DKFZp686N0351, DKFZp686P1838, FLJ40466, PARP-1, PARP-7, PARP7, pART14 |
Other Names | TCDD-inducible poly [ADP-ribose] polymerase, 2.4.2.30, ADP-ribosyltransferase diphtheria toxin-like 14, ARTD14, Poly [ADP-ribose] polymerase 7, PARP-7, TIPARP, PARP7 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-TIPARP antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | TIPARP antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TIPARP {ECO:0000303|PubMed:12851707, ECO:0000312|HGNC:HGNC:23696} |
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Function | ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate, aspartate and cysteine residues on target proteins (PubMed:23275542, PubMed:25043379, PubMed:30373764). Acts as a negative regulator of AHR by mediating mono-ADP-ribosylation of AHR, leading to inhibit transcription activator activity of AHR (PubMed:23275542, PubMed:30373764). |
Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
References
Mehrle,A., Nucleic Acids Res. 34 (DATABASE ISSUE), D415-D418 (2006)Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:MacPherson, L. et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation. Nucleic Acids Res. 41, 1604-21 (2013). ICC/IF, IP, Human, Bovine, Dog, Horse, Pig, Rabbit, Rat, Mouse23275542
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