|Other Accession||NM_024140, NP_077054|
|Reactivity||Human, Mouse, Rat, Goat, Horse, Bovine, Dog|
|Predicted||Pig, Chicken, Guinea Pig, Dog|
|Other Names||Neurogranin, Ng, Protein kinase C substrate 7.5 kDa protein, RC3, NEUG(55-78), Nrgn|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Nrgn antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Nrgn antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates the affinity of calmodulin for calcium. Involved in synaptic plasticity and spatial learning (By similarity).|
|Cellular Location||Cytoplasm. Cell junction, synapse. Cell projection, dendritic spine. Note=Restricted to dendritic spines of a subset of neurons|
|Tissue Location||Highly enriched in brain with restricted expression in neuronal subsets primarily in the cortex, striatum, and hippocampus as well as certain nuclei within the thalamus, hypothalamus and olfactory bulb. Accumulates postsynaptically in dendritic spines of neostriatal neurons|
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