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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Pthlh antibody - middle region   

Pthlh antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Pthlh antibody - middle region AI10577
    WB Suggested Anti-Pthlh Antibody Titration: 1 μg/ml
    Positive Control: Mouse Brain lysate
  • IHC - Pthlh antibody - middle region AI10577
    Immunohistochemistry with Lung tissue at an antibody concentration of 5μg/ml using anti-Pthlh antibody (AI1577)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P22858
Other Accession NM_008970, NP_032996
Reactivity Human, Mouse, Rat, Goat, Sheep, Horse, Bovine, Dog
Predicted Human, Mouse, Pig, Chicken, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 16kDa
Additional Information
Alias Symbol PTH-like, Pthrp
Other Names Parathyroid hormone-related protein, PTH-rP, PTHrP, Parathyroid hormone-like protein, PLP, Osteostatin, Pthlh, Pthrp
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Pthlh antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPthlh antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pthlh
Synonyms Pthrp
Function Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath.
Cellular Location Cytoplasm. Nucleus. Secreted
Research Areas
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$ 293.00
Cat# AI10577
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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