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RGS6 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P49758 |
| Other Accession | NM_004296, NP_004287 |
| Reactivity | Human, Mouse, Rat |
| Predicted | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 54kDa |
| Gene ID | 9628 |
|---|---|
| Alias Symbol | DKFZp313G1241, FLJ43552, GAP, MGC142132 |
| Other Names | Regulator of G-protein signaling 6, RGS6, S914, RGS6 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-RGS6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | RGS6 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RGS6 |
|---|---|
| Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP- bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509). |
| Cellular Location | Cytoplasm. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Nucleus Cell membrane {ECO:0000250|UniProtKB:Q9Z2H2}. Note=Interaction with GNB5 mediates translocation to the nucleus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Gu,J., (2006) Cancer 106 (12), 2716-2724 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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