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RGS17 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9UGC6 |
| Other Accession | NM_012419, NP_036551 |
| Reactivity | Human, Mouse, Rat, Pig, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Pig, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 23kDa |
| Gene ID | 26575 |
|---|---|
| Alias Symbol | RGS-17, RGSZ2, hRGS17 |
| Other Names | Regulator of G-protein signaling 17, RGS17, RGS17 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-RGS17 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | RGS17 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RGS17 |
|---|---|
| Synonyms | RGSZ2 {ECO:0000303|PubMed:15096504} |
| Function | Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:15096504). Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity). |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:Q9QZB0}. Synapse, synaptosome {ECO:0000250|UniProtKB:Q9QZB0}. Nucleus {ECO:0000250|UniProtKB:Q9QZB0}. Cytoplasm {ECO:0000250|UniProtKB:Q9QZB0} |
| Tissue Location | Predominantly expressed in the cerebellum. Also expressed in the cortex and medulla. Weakly expressed in a number of peripheral tissues notably spleen, lung and leukocytes |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI10601
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