|Other Accession||NM_029979, NP_084255|
|Reactivity||Human, Mouse, Rat, Pig, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Pig, Bovine, Guinea Pig, Dog|
|Alias Symbol||0710005M05Rik, A430106H13Rik, AW046487, HLS5, Mair, NC8, mKIAA1098|
|Other Names||Tripartite motif-containing protein 35, Hemopoietic lineage switch protein 5, Macrophage-derived apoptosis-inducing RBCC protein, Protein MAIR, Protein Nc8, Trim35, Hls5, Kiaa1098, Mair|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-Trim35 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Trim35 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||Hls5, Kiaa1098, Mair|
|Function||Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth (By similarity). Implicated in the cell death mechanism (PubMed:12692137, PubMed:14662771).|
|Cellular Location||Cytoplasm. Nucleus. Note=Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies in transfected COS and HeLa cells.|
|Tissue Location||Widely expressed. Highly expressed in brain, heart, kidney, spleen, skeletal muscle, lung and thymus. Lower expression found in stomach, large intestine and bone marrow|
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