|Other Accession||NM_000966, NP_000957|
|Reactivity||Human, Mouse, Rat, Rabbit, Sheep, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Pig, Bovine, Dog|
|Alias Symbol||NR1B3, RARC|
|Other Names||Retinoic acid receptor gamma, RAR-gamma, Nuclear receptor subfamily 1 group B member 3, RARG, NR1B3|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-RARG antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RARG antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Dey,N., (2007) Mol. Cell. Biol. 27 (11), 4179-4197 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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