|Other Accession||NM_000723, NP_000714|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Zebrafish, Pig, Bovine|
|Alias Symbol||CAB1, CACNLB1, CCHLB1, MGC41896|
|Other Names||Voltage-dependent L-type calcium channel subunit beta-1, CAB1, Calcium channel voltage-dependent subunit beta 1, CACNB1, CACNLB1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-CACNB1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CACNB1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.|
|Cellular Location||Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side|
|Tissue Location||Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle|
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Provided below are standard protocols that you may find useful for product applications.
Hogan,K., et al., (1999) Neurosci. Lett. 277 (2), 111-114Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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