|Other Accession||NM_000744, NP_000735|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Zebrafish, Bovine|
|Alias Symbol||BFNC, EBN, EBN1, NACRA4, NACHR, NACHRA4|
|Other Names||Neuronal acetylcholine receptor subunit alpha-4, CHRNA4, NACRA4|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-CHRNA4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CHRNA4 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.|
|Cellular Location||Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor|
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Provided below are standard protocols that you may find useful for product applications.
Fedi,M., (2008) J. Clin. Endocrinol. Metab. 93 (2), 634-637 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:Ishizuka, T., Ozawa, A., Goshima, H. & Watanabe, Y. Involvement of nicotinic acetylcholine receptor in the proliferation of mouse induced pluripotent stem cells. Life Sci. 90, 637-48 (2012). WB, Mouse, Guinea pig, Human, Rat, Dog, Zebrafish, Bovine, H, Rabbit22483693
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