|Other Accession||NM_008426, NP_032452|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Mouse, Rat, Pig, Chicken|
|Alias Symbol||GIRK1, Kcnf3, Kir3.1, MGC124233, MGC124234|
|Other Names||G protein-activated inward rectifier potassium channel 1, GIRK-1, Inward rectifier K(+) channel Kir3.1, Potassium channel, inwardly rectifying subfamily J member 3, Kcnj3, Girk1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Kcnj3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Kcnj3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
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