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KCNN4 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - KCNN4 antibody - C-terminal region AI10789

    Host: Rabbit
    Target Name: KCNN4
    Sample Tissue: HepG2
    Antibody Dilution: 1.0μg/ml
    detail
  • WB - KCNN4 antibody - C-terminal region AI10789

    Host: Rabbit
    Target Name: KCNN4
    Sample Tissue: Jurkat
    Antibody Dilution: 1.0μg/ml
    detail
  • WB - KCNN4 antibody - C-terminal region AI10789

    Host: Rabbit
    Target Name: KCNN4
    Sample Tissue: MCF7
    Antibody Dilution: 1.0μg/ml
    detail
  • WB - KCNN4 antibody - C-terminal region AI10789

    Host: Rabbit
    Target Name: KCNN4
    Sample Tissue: Hela
    Antibody Dilution: 1.0μg/ml
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O15554
Other Accession NM_002250, NP_002241
Reactivity Human, Rat, Pig, Horse, Bovine
Predicted Human, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 48kDa
Additional Information
Gene ID 3783
Alias Symbol IK1, IKCA1, KCA4, KCa3.1, SK4, hIKCa1, hKCa4, hSK4
Other Names Intermediate conductance calcium-activated potassium channel protein 4, SK4, SKCa 4, SKCa4, IKCa1, IK1, KCa3.1, KCa4, Putative Gardos channel, KCNN4, IK1, IKCA1, KCA4, SK4
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-KCNN4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsKCNN4 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNN4
Synonyms IK1, IKCA1, KCA4, SK4
Function Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells (PubMed:17157250, PubMed:18796614). Plays a role in the late stages of EGF-induced macropinocytosis (PubMed:24591580).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Widely expressed in non-excitable tissues.
Research Areas
Citations (0)
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References

Gao,Y., (2008) J. Biol. Chem. 283 (14), 9049-9059 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 389.00
Cat# AI10789
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