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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CLCA2 antibody - C-terminal region   

CLCA2 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - CLCA2 antibody - C-terminal region AI10801

    WB Suggested Anti-CLCA2 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: THP-1 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UQC9
Other Accession NM_006536, NP_006527
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog
Predicted Human, Rabbit, Pig, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 104kDa
Additional Information
Gene ID 9635
Alias Symbol CACC, CACC3, CLCRG2, CaCC-3, FLJ97885
Other Names Calcium-activated chloride channel regulator 2, 3.4.-.-, Calcium-activated chloride channel family member 2, hCLCA2, Calcium-activated chloride channel protein 3, CaCC-3, hCaCC-3, Calcium-activated chloride channel regulator 2, 109 kDa form, Calcium-activated chloride channel regulator 2, 35 kDa form, CLCA2, CACC3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CLCA2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCLCA2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLCA2
Synonyms CACC3
Function Plays a role in modulating chloride current across the plasma membrane in a calcium-dependent manner, and cell adhesion. Involved in basal cell adhesion and/or stratification of squamous epithelia. May act as a tumor suppressor in breast and colorectal cancer. Plays a key role for cell adhesion in the beginning stages of lung metastasis via the binding to ITGB4.
Cellular Location Cell membrane; Single-pass type I membrane protein. Basal cell membrane; Single-pass type I membrane protein Cell junction
Tissue Location Expressed in cornea, skin, vagina, esophagus, and larynx (at protein level). Expressed in trachea and mammary gland. Weakly expressed in testis and kidney. Highly expressed in corneal epithelium, colon and trachea. Moderately expressed in brain, urogenital organs, bladder, uterus and prostate. Highly expressed in tissues containing stratified epithelium including cornea, esophagus, larynx, skin and vagina than those tissues which contain only epithelial monolayers. Expressed in normal breast epithelium but not in breast cancer. Highly expressed during epithelial stratification. Expressed in endothelial cells of lung. Expressed selectively in endothelia of small pulmonary arteries, arterioles, and subpleural and interlobular venules
Research Areas
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$ 293.00
Cat# AI10801
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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