|Other Accession||NM_017901, NP_060371|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rabbit, Pig, Chicken, Bovine|
|Alias Symbol||FLJ20612, KIAA1169, TPC1|
|Other Names||Two pore calcium channel protein 1, Voltage-dependent calcium channel protein TPC1, TPCN1, KIAA1169, TPC1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-TPCN1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TPCN1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal and endosomal membrane.|
|Cellular Location||Lysosome membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein|
|Tissue Location||Highest expression found in the heart and kidney, and lowest expression found in the spleen|
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Provided below are standard protocols that you may find useful for product applications.
Clapham,D.E. (2005) Pharmacol. Rev. 57 (4), 451-454Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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