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Trpv6 antibody - middle region

Rabbit Polyclonal Antibody

  • IHC - Trpv6 antibody - middle region AI10813
    Sample Type: hRetinal pigment epithelial cells Green: primary Red: nuclear Primary Dilution: 1:200
    Secondary Antibody: goat anti-rabbit-Alexa 488 Secondary Dilution: 1:500 Image
    Submitted by: Brian Kennedy Indiana University Northwest See Customer Feedback tab for detailed information.
  • WB - Trpv6 antibody - middle region AI10813
    Trpv6 antibody - middle region (AI10813) validated by WB using Rat Brain lysate at 1μg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9R186
Other Accession NM_053686, NP_446138
Reactivity Human, Mouse, Rat, Rabbit, Horse, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 83kDa
Additional Information
Gene ID 114246
Alias Symbol CaT1, Ecac2, Otrpc3
Other Names Transient receptor potential cation channel subfamily V member 6, TrpV6, Calcium transport protein 1, CaT1, Epithelial calcium channel 2, ECaC2, Trpv6
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Trpv6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTrpv6 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Trpv6
Function Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues, including Ca(2+) reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin- dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity).
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q91WD2, ECO:0000250|UniProtKB:Q9H1D0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q91WD2}
Tissue Location Expressed in duodenum, proximal jejunum, cecum, and colon.
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$ 293.00
Cat# AI10813
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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