|Other Accession||NM_022659, NP_073150|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog|
|Predicted||Human, Rat, Pig, Chicken, Horse, Dog|
|Alias Symbol||COE2, EBF-2, FLJ11500, O/E-3, OE-3|
|Other Names||Transcription factor COE2, Early B-cell factor 2, EBF-2, EBF2, COE2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-EBF2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||EBF2 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt- responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Nusbaum,C., (2006) Nature 439 (7074), 331-335 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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