|Other Accession||NM_016377, NP_057461|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog|
|Alias Symbol||AKAP18, AKAP15|
|Other Names||A-kinase anchor protein 7 isoform gamma, AKAP-7 isoform gamma, A-kinase anchor protein 18 kDa, AKAP 18, Protein kinase A-anchoring protein 7 isoform gamma, PRKA7 isoform gamma, AKAP7, AKAP18|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 100 ul of distilled water. Final anti-AKAP7 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||AKAP7 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane- associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.|
|Cellular Location||Nucleus. Cytoplasm|
|Tissue Location||Expressed in brain, heart, lung, pancreas and placenta.|
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Provided below are standard protocols that you may find useful for product applications.
Brown,R.L., et al., (2003) Biochem. Biophys. Res. Commun. 306 (2), 394-401Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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