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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   RUNX2 antibody - middle region   

RUNX2 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - RUNX2 antibody - middle region AI11017

    WB Suggested Anti-RUNX2 Antibody Titration: 1.25μg/ml
    ELISA Titer: 1:1562500
    Positive Control: Jurkat cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13950
Other Accession NM_001024630, NP_001019801
Reactivity Human, Mouse, Rat, Rabbit, Bovine, Dog
Predicted Mouse, Rat, Rabbit, Pig, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 57kDa
Additional Information
Gene ID 860
Alias Symbol CCD, AML3, CCD1, OSF2, CBFA1, OSF-2, PEA2aA, PEBP2A1, PEBP2A2, PEBP2aA, PEBP2aA1
Other Names Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit alpha-1, CBF-alpha-1, Oncogene AML-3, Osteoblast-specific transcription factor 2, OSF-2, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEA2-alpha A, PEBP2-alpha A, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit, RUNX2, AML3, CBFA1, OSF2, PEBP2A
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-RUNX2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRUNX2 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RUNX2
Synonyms AML3, CBFA1, OSF2, PEBP2A
Function Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'- PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.
Cellular Location Nucleus.
Tissue Location Specifically expressed in osteoblasts.
Research Areas
Citations (0)

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Guo,J., et al., (2006) Dev. Biol. 292 (1), 116-128Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:Schuchardt, M. et al. Uridine adenosine tetraphosphate activation of the purinergic receptor P2Y enhances in vitro vascular calcification. Kidney Int. 81, 256-65 (2012). WB, Mouse, Bovine, Rat, Rabbit, Guinea pig, Dog, Human21956191

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$ 232.00
Cat# AI11017
(40 western blots)
Availability: 2-3 days
Bulk Size
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