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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Zebrafish   >   MCM8 antibody - N-terminal region   

MCM8 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - MCM8 antibody - N-terminal region AI11020

    WB Suggested Anti-MCM8 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:1562500
    Positive Control: OVCAR-3 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UJA3
Other Accession NM_032485, NP_115874
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 94kDa
Additional Information
Gene ID 84515
Alias Symbol C20orf154, MGC119522, MGC119523, MGC12866, MGC4816, REC, dJ967N21.5
Other Names DNA helicase MCM8,, Minichromosome maintenance 8, MCM8, C20orf154
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-MCM8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMCM8 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MCM8
Synonyms C20orf154
Function Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8- MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. May also play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex (ORC). Binds chromatin throughout the cell cycle.
Cellular Location Nucleus. Note=Localizes to nuclear foci and colocalizes with RAD51
Tissue Location Highest levels in placenta, lung and pancreas. Low levels in skeletal muscle and kidney. Expressed in various tumors with highest levels in colon and lung cancers
Research Areas
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$ 293.00
Cat# AI11020
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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