|Other Accession||NM_007524, NP_031550|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog|
|Predicted||Rat, Zebrafish, Pig, Bovine, Dog|
|Alias Symbol||NKX3.2, Nkx-3.2, Nkx3-2, Bapx1|
|Other Names||Homeobox protein Nkx-3.2, Bagpipe homeobox protein homolog 1, Homeobox protein NK-3 homolog B, Nkx3-2, Bapx1, Nkx-3.2, Nkx3b|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Bapx1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Bapx1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||Bapx1, Nkx-3.2, Nkx3b|
|Function||Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus.|
|Tissue Location||Expressed widely in mesoderm at the gastroduodenal junction (at protein level). Expressed in visceral mesoderm and embryonic skeleton. Expression is restricted to immature proliferative chondrocytes during endochondral ossification.|
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Provided below are standard protocols that you may find useful for product applications.
Provot,S., (2006) Development 133 (4), 651-662 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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