MEF2B antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | O55087 |
Other Accession | NM_008578, NP_032604 |
Reactivity | Mouse, Rat |
Predicted | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 38kDa |
Alias Symbol | AI451606 |
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Other Names | Myocyte-specific enhancer factor 2B, Mef2b |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 100 ul of distilled water. Final anti-MEF2B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | MEF2B antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Mef2b |
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Function | Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00251}. |
Tissue Location | Highest expression found in embryonic heart and skeletal muscle. Low levels found in adult spleen, lung and testis while no expression is found in adult heart, brain or skeletal muscle |
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Provided below are standard protocols that you may find useful for product applications.
References
Allen,D.L., et al., (2005) J. Biol. Chem. 280 (17), 17126-17134Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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