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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Tfam antibody - C-terminal region   

Tfam antibody - C-terminal region

Rabbit Polyclonal Antibody

  • IHC - Tfam antibody - C-terminal region AI11089
    Mouse testicle
  • WB - Tfam antibody - C-terminal region AI11089

    WB Suggested Anti-Tfam Antibody Titration: 0.2-1 μg/ml
    Positive Control: SP2/0 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P40630
Other Accession NM_009360, NP_033386
Reactivity Mouse, Rat, Rabbit, Bovine
Predicted Mouse, Rat, Rabbit, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 27kDa
Additional Information
Gene ID 21780
Alias Symbol AI661103, Hmgts, mtTFA, tsHMG
Other Names Transcription factor A, mitochondrial, mtTFA, Testis-specific high mobility group protein, TS-HMG, Tfam, Hmgts
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Tfam antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTfam antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tfam
Synonyms Hmgts
Function Isoform Mitochondrial binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. Isoform Nuclear may also function as a transcriptional activator or may have a structural role in the compaction of nuclear DNA during spermatogenesis.
Cellular Location Isoform Mitochondrial: Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid
Tissue Location The mitochondrial isoform is widely expressed while the nuclear isoform is testis-specific
Research Areas
Citations (0)

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Noack,H., (2006) Biochim. Biophys. Acta 1760 (2), 141-150 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 293.00
Cat# AI11089
(40 western blots)
Availability: 2-3 days
Bulk Size
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