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Ttf1 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Ttf1 antibody - N-terminal region AI11093

    WB Suggested Anti-Ttf1 Antibody Titration: 0.2-1 μg/ml
    Positive Control: Mouse Heart
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q62187
Other Accession NM_009442, NP_033468
Reactivity Mouse, Rat
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 98 KDa
Additional Information
Gene ID 22130
Alias Symbol AV245725
Other Names Transcription termination factor 1, TTF-1, RNA polymerase I termination factor, Transcription termination factor I, TTF-I, mTFF-I, Ttf1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Ttf1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTtf1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ttf1
Function Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin (PubMed:7720715, PubMed:9267035, PubMed:15292447, PubMed:9049305). Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription (PubMed:15292447, PubMed:20513429). Interaction with BAZ2A/TIP5 recovers DNA-binding activity (PubMed:15292447).
Cellular Location Nucleus. Nucleus, nucleolus Nucleus, nucleoplasm. Note=May be localized to the nucleolus in an NPM1/B23-dependent manner (PubMed:20513429). May be displaced from the nucleolus into the nucleoplasm in an CDKN2A/ARF-dependent manner (PubMed:20513429). May shuttle back and forth from nucleoplasm to nucleolus (PubMed:20513429)
Citations (0)
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$ 389.00
Cat# AI11093
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