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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Hira antibody - middle region   

Hira antibody - middle region

Rabbit Polyclonal Antibody

  • WB - Hira antibody - middle region AI11112

    WB Suggested Anti-Hira Antibody Titration: 0.2-1 μg/ml
    Positive Control: Mouse Brain
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q61666
Other Accession NM_010435, NP_034565
Reactivity Human, Mouse, Rat, Rabbit, Horse, Dog
Predicted Human, Mouse, Rabbit, Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 112 KDa
Additional Information
Gene ID 15260
Alias Symbol AA138857, D16Ertd95e, N28177, Tuple1
Other Names Protein HIRA, TUP1-like enhancer of split protein 1, Hira, Tuple1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Hira antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsHira antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Hira
Synonyms Tuple1
Function Required for the periodic repression of histone gene transcription during the cell cycle (By similarity). Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Cellular Location Nucleus. Nucleus, PML body. Note=Primarily, though not exclusively, localized to the nucleus (By similarity). Localizes to PML bodies immediately prior to onset of senescence (By similarity) Localizes specifically to the male nucleus in fertilized eggs This localization persists from the initiation of sperm nucleus decondensation to pronucleus formation. {ECO:0000250, ECO:0000269|PubMed:15922569, ECO:0000269|PubMed:9731536}
Tissue Location Expressed in cerebrum, cerebellum, heart, kidney, liver, lung and spleen
Research Areas
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$ 293.00
Cat# AI11112
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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