|Application ||WB, IHC|
|Other Accession||NM_011489, NP_035619|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Sheep, Horse, Bovine, Dog|
|Predicted||Human, Rabbit, Pig, Chicken, Horse, Dog|
|Other Names||Signal transducer and activator of transcription 5B, Stat5b|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 100 ul of distilled water. Final anti-STAT5B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||STAT5B antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription (PubMed:11773439). Positively regulates hematopoietic/erythroid differentiation (By similarity).|
|Cellular Location||Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation|
|Tissue Location||In the virgin, found in most tissues. Particularly abundant in muscle tissue of virgin and lactating females, and of males|
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Provided below are standard protocols that you may find useful for product applications.
Laloraya,M., et al., (2006) Diabetes 55 (3), 734-741Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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