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>   home   >   Products   >   Primary Antibodies   >   Nr2c1 antibody - N-terminal region   

Nr2c1 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Nr2c1 antibody - N-terminal region AI11142

    WB Suggested Anti-Nr2c1 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: Mouse Lung
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8VIJ4
Other Accession NM_011629, NP_035759
Reactivity Human, Mouse, Rat, Horse, Yeast, Bovine, Dog
Predicted Human, Mouse, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 65kDa
Additional Information
Gene ID 252924
Alias Symbol 4831444H07Rik, 80.3, Eenr, TR2, Tr2-11
Other Names Nuclear receptor subfamily 2 group C member 1, Orphan nuclear receptor TR2, Testicular receptor 2, Nr2c1, Tr2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Nr2c1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsNr2c1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Nr2c1
Synonyms Tr2
Function Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes including ESR1 and RARB. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Also activator of OCT4 gene expression. Plays a fundamental role in early embryogenesis and regulates embryonic stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}. Nucleus, PML body. Note=Recruited by HDAC3, after all-trans retinoic acid stimulated MAPK1-mediated Thr-210 phosphorylation, to PML bodies for subsequent sumoylation
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$ 293.00
Cat# AI11142
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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