|Other Accession||NM_001025562, NP_001020733|
|Alias Symbol||A730013B20Rik, MPUS1, mPus1p|
|Other Names||tRNA pseudouridine synthase A, mitochondrial, 22.214.171.124, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I, Pus1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Pus1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Pus1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Converts specific uridines to PSI in a number of tRNA substrates. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Involved in regulation of nuclear receptor activity possibly through pseudouridylation of SRA1 RNA. Isoforms 3 and 4 do not form pseudouridine when expressed in vitro.|
|Cellular Location||Isoform 1: Mitochondrion.|
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