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Pus1 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9WU56 |
| Other Accession | NM_001025562, NP_001020733 |
| Reactivity | Mouse, Rat |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 44kDa |
| Gene ID | 56361 |
|---|---|
| Alias Symbol | A730013B20Rik, MPUS1, mPus1p |
| Other Names | tRNA pseudouridine synthase A, mitochondrial, 5.4.99.12, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I, Pus1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Pus1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Pus1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Pus1 {ECO:0000303|PubMed:10094309, ECO:0000312|MGI:MGI:1929237} |
|---|---|
| Function | Pseudouridylate synthase that catalyzes pseudouridylation of tRNAs and mRNAs (PubMed:10094309, PubMed:15327771, PubMed:27197761). Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA (PubMed:10094309). Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3' (By similarity). Acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions (By similarity). Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing (By similarity). Involved in regulation of nuclear receptor activity through pseudouridylation of SRA1 mRNA (PubMed:15327771). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q9Y606}. Cytoplasm {ECO:0000250|UniProtKB:Q9Y606}. Mitochondrion {ECO:0000250|UniProtKB:Q9Y606} |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI11167
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