Ilf2 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9CXY6 |
Other Accession | NM_026374, NP_080650 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 42kDa |
Gene ID | 67781 |
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Alias Symbol | 6230405A16Rik, TEG-267, Tex261, Tex267 |
Other Names | Interleukin enhancer-binding factor 2, Nuclear factor of activated T-cells 45 kDa, Ilf2, Nf45 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Ilf2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Ilf2 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Ilf2 |
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Synonyms | Nf45 |
Function | Chromatin-interacting protein that forms a stable heterodimer with interleukin enhancer-binding factor 3/ILF3 and plays a role in several biological processes including transcription, innate immunity or cell growth (PubMed:10574923). Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus. Together with ILF3, forms an RNA-binding complex that is required for mitotic progression and cytokinesis by regulating the expression of a cluster of mitotic genes. Mechanistically, competes with STAU1/STAU2- mediated mRNA decay. Also plays a role in the inhibition of various viruses including Japanese encephalitis virus or enterovirus 71 (By similarity) (PubMed:10574923). |
Cellular Location | Nucleus, nucleolus {ECO:0000250|UniProtKB:Q12905}. Cytoplasm {ECO:0000250|UniProtKB:Q12905}. Nucleus {ECO:0000250|UniProtKB:Q12905} Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. {ECO:0000250|UniProtKB:Q12905} |
Tissue Location | Expressed in brain, kidney and ovary; highly expressed in testis, particularly within pachytene cells |
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