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Glis1 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8K1M4 |
| Other Accession | NM_147221, NP_671754 |
| Reactivity | Mouse, Rat, Rabbit, Pig, Bovine, Dog |
| Predicted | Mouse, Rat, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 84kDa |
| Gene ID | 230587 |
|---|---|
| Alias Symbol | Gli5, Gli6, GliH1 |
| Other Names | Zinc finger protein GLIS1, GLI-similar 1, Gli homologous protein 1, GliH1, Glis1 {ECO:0000312|MGI:MGI:2386723}, Gli5 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Glis1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Glis1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Glis1 {ECO:0000312|MGI:MGI:2386723} |
|---|---|
| Synonyms | Gli5 |
| Function | Acts both as a repressor and an ctivator of transcription (PubMed:12042312, PubMed:12385751, PubMed:21654807). Binds to the consensus sequence 5'-GACCACCCAC-3' (PubMed:12042312). By controlling the expression of genes involved in cell differentiation inhibits the lineage commitment of multipotent cells (PubMed:21654807, PubMed:30544251). Prevents, for instance, the differentiation of multipotent mesenchymal cells into adipocyte and osteoblast (PubMed:30544251). |
| Cellular Location | Nucleus. |
| Tissue Location | In the adult, expressed highly in placenta and kidney and at lower levels in the testis, brain, colon, brown fat tissue and thymus. During embryo development, expressed in the frontal nasal region, branchial arches, somites, vibrissal and hair follicles, limb buds, craniofacial regions, ventral part of the tail, intervertebral disks, teeth, eyes and kidney |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI11235
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