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Gtf2h3 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Gtf2h3 antibody - N-terminal region AI11268

    WB Suggested Anti-Gtf2h3 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: Mouse Spleen
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q8VD76
Other Accession NM_181410, NP_852075
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine
Predicted Mouse, Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 34kDa
Additional Information
Gene ID 209357
Alias Symbol 34kDa, 5033417D07Rik, BTF2, C730029A10, D5Ertd679e, TFIIH, BTF2 p34
Other Names General transcription factor IIH subunit 3, Basic transcription factor 2 34 kDa subunit, BTF2 p34, General transcription factor IIH polypeptide 3, TFIIH basal transcription factor complex p34 subunit, Gtf2h3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Gtf2h3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsGtf2h3 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Gtf2h3
Function Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q13889}.
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$ 389.00
Cat# AI11268
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