Taf3 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q5HZG4 |
Other Accession | NM_027748, NP_082024 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Bovine, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 105kDa |
Gene ID | 209361 |
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Alias Symbol | 140kDa, 4933439M23Rik, AW539625, TAF140, TAFII-140, TAFII140, mTAFII140 |
Other Names | Transcription initiation factor TFIID subunit 3, 140 kDa TATA box-binding protein-associated factor, TBP-associated factor 3, Transcription initiation factor TFIID 140 kDa subunit, TAF(II)140, TAF140, TAFII-140, TAFII140, Taf3 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Taf3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Taf3 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Taf3 |
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Function | The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (By similarity). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (By similarity). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (By similarity). The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C (By similarity). TAF3 forms the TFIID-A module together with TAF5 and TBP (By similarity). Required in complex with TBPL2 for the differentiation of myoblasts into myocytes (PubMed:17704303). The TAF3- TBPL2 complex replaces TFIID at specific promoters at an early stage in the differentiation process (PubMed:17704303). |
Cellular Location | Nucleus. |
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