Esrp2 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8K0G8 |
Other Accession | NM_176838, NP_789808 |
Reactivity | Human, Mouse, Rat, Rabbit, Bovine, Dog |
Predicted | Mouse, Rat, Pig, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 77kDa |
Gene ID | 77411 |
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Alias Symbol | 9530027K23Rik, Rbm35b |
Other Names | Epithelial splicing regulatory protein 2, RNA-binding motif protein 35B, RNA-binding protein 35B, Esrp2, Rbm35b |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Esrp2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Esrp2 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Esrp2 |
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Synonyms | Rbm35b |
Function | mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity). |
Cellular Location | Nucleus. |
Tissue Location | Epithelial cell-specific. |
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