|Other Accession||NM_009212, NP_033238|
|Reactivity||Human, Mouse, Rat, Bovine, Dog|
|Predicted||Mouse, Rat, Pig, Bovine|
|Alias Symbol||AEP, Catf1, RIPE3b1, Smbp-2, Smbp2, Smubp2, nmd, sma|
|Other Names||DNA-binding protein SMUBP-2, 220.127.116.11, 18.104.22.168, ATP-dependent helicase IGHMBP2, Cardiac transcription factor 1, CATF1, Immunoglobulin mu-binding protein 2, Ighmbp2, Smbp-2, Smbp2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Ighmbp2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Ighmbp2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver- type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region (By similarity). May be involved in translation. DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr.|
|Cellular Location||Nucleus. Cytoplasm. Cell projection, axon. Note=Colocalizes with the translation initiation factor EIF4G2|
|Tissue Location||In all tissues examined.|
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