Meis1 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q60954 |
Other Accession | NM_010789, NP_034919 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Chicken, Horse, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 51kDa |
Gene ID | 17268 |
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Alias Symbol | C530044H18Rik, Evi8 |
Other Names | Homeobox protein Meis1, Myeloid ecotropic viral integration site 1, Meis1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Meis1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Meis1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Meis1 |
---|---|
Function | Acts as a transcriptional regulator of PAX6. Also acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:10082572, ECO:0000269|PubMed:15882575} |
Tissue Location | Expressed at high levels in the lung with lower levels detected in the heart and brain. Expressed in pancreatic islets (beta-cells and non-beta-cells) (PubMed:21059917) |
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