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MNAT1 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - MNAT1 antibody - C-terminal region AI11372

    WB Suggested Anti-MNAT1 Antibody Titration: 1.25μg/ml
    Positive Control: Jurkat cell lysate
    MNAT1 is supported by BioGPS gene expression data to be expressed in Jurkat
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51948
Other Accession NM_002431, NP_002422
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog
Predicted Human, Rat, Zebrafish, Pig, Chicken, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 36kDa
Additional Information
Gene ID 4331
Alias Symbol MAT1, TFB3, CAP35, RNF66
Other Names CDK-activating kinase assembly factor MAT1, CDK7/cyclin-H assembly factor, Cyclin-G1-interacting protein, Menage a trois, RING finger protein 66, RING finger protein MAT1, p35, p36, MNAT1, CAP35, MAT1, RNF66
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-MNAT1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMNAT1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MNAT1
Synonyms CAP35, MAT1, RNF66
Function Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
Cellular Location Nucleus.
Tissue Location Highest levels in colon and testis. Moderate levels are present thymus, prostate, ovary, and small intestine The lowest levels are found in spleen and leukocytes
Research Areas
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Zhou,M., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (22), 12666-12671Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 232.00
Cat# AI11372
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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