|Other Accession||NM_003106, NP_003097|
|Reactivity||Human, Mouse, Rat, Zebrafish, Pig, Goat, Bovine|
|Predicted||Human, Mouse, Rat, Rabbit, Zebrafish, Chicken, Sheep|
|Alias Symbol||ANOP3, MGC2413, MCOPS3|
|Other Names||Transcription factor SOX-2, SOX2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 100 ul of distilled water. Final anti-SOX2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SOX2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Lei,J.X., (2005) Cell Death Differ. 12 (11), 1368-1377 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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