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ZNF259 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - ZNF259 antibody - N-terminal region AI11408

    WB Suggested Anti-ZNF259 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: Jurkat cell lysate
    ZNF259 is supported by BioGPS gene expression data to be expressed in Jurkat
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75312
Other Accession NM_003904, NP_003895
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog
Predicted Human, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 51kDa
Additional Information
Gene ID 8882
Alias Symbol ZPR1
Other Names Zinc finger protein ZPR1, Zinc finger protein 259, ZPR1, ZNF259
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-ZNF259 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsZNF259 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZPR1
Synonyms ZNF259
Function Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of cellular pre-mRNAs. May be involved in H(2)O(2)-induced neuronal cell death.
Cellular Location Nucleus. Nucleus, nucleolus. Nucleus, gem. Nucleus, Cajal body. Cytoplasm, perinuclear region. Cytoplasm Cell projection, axon. Cell projection, growth cone. Note=Colocalized with SMN1 in Gemini of coiled bodies (gems), Cajal bodies, axon and growth cones of neurons (By similarity). Localized predominantly in the cytoplasm in serum- starved cells growth arrested in G0 of the mitotic cell cycle Localized both in the nucleus and cytoplasm at the G1 phase of the mitotic cell cycle. Accumulates in the subnuclear bodies during progression into the S phase of the mitotic cell cycle. Diffusely localized throughout the cell during mitosis. Colocalized with NPAT and SMN1 in nuclear bodies including gems (Gemini of coiled bodies) and Cajal bodies in a cell cycle-dependent manner Translocates together with EEF1A1 from the cytoplasm to the nucleolus after treatment with mitogens. Colocalized with EGFR in the cytoplasm of quiescent cells. Translocates from the cytoplasm to the nucleus in a epidermal growth factor (EGF)-dependent manner.
Tissue Location Expressed in fibroblast; weakly expressed in fibroblast of spinal muscular atrophy (SMA) patients
Research Areas
Citations (0)

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Gangwani,L., et al., (2005) Mol. Cell. Biol. 25 (7), 2744-2756Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 293.00
Cat# AI11408
(40 western blots)
Availability: 2-3 days
Bulk Size
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