Nfkbil1 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | O88995 |
Other Accession | NM_010909, NP_035039 |
Reactivity | Human, Mouse, Rat, Pig, Goat, Horse, Bovine, Dog |
Predicted | Mouse, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 43kDa |
Gene ID | 18038 |
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Alias Symbol | Def-7, IKBL |
Other Names | NF-kappa-B inhibitor-like protein 1, Inhibitor of kappa B-like protein, I-kappa-B-like protein, IkappaBL, Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1, Nfkbil1, Ikbl |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Nfkbil1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Nfkbil1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Nfkbil1 |
---|---|
Synonyms | Ikbl |
Function | Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous pro-inflammatory stimuli (By similarity). |
Cellular Location | Nucleus. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus (By similarity). |
Tissue Location | High expression found in heart muscle, liver, kidney and skin. Not detected in spleen, lung and brain |
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