|Other Accession||NM_010909, NP_035039|
|Reactivity||Human, Mouse, Rat, Pig, Goat, Horse, Bovine, Dog|
|Predicted||Mouse, Bovine, Dog|
|Alias Symbol||Def-7, IKBL|
|Other Names||NF-kappa-B inhibitor-like protein 1, Inhibitor of kappa B-like protein, I-kappa-B-like protein, IkappaBL, Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1, Nfkbil1, Ikbl|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Nfkbil1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Nfkbil1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon- regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli (By similarity).|
|Cellular Location||Nucleus. Note=Nuclear localization with a speckled expression pattern in some cells Colocalizes with CACTIN in the nucleus (By similarity)|
|Tissue Location||High expression found in heart muscle, liver, kidney and skin. Not detected in spleen, lung and brain|
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