|Other Accession||NM_005171, NP_005162|
|Reactivity||Human, Mouse, Rat, Rabbit, Sheep, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Bovine, Dog|
|Alias Symbol||TREB36, EWS-ATF1, FUS/ATF-1|
|Other Names||Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1, Activating transcription factor 1, Protein TREB36, ATF1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ATF1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ATF1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.|
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Provided below are standard protocols that you may find useful for product applications.
Somers,G.R., et al., (2005) Am. J. Surg. Pathol. 29 (12), 1673-1679Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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