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>   home   >   Products   >   Primary Antibodies   >   Microbiology   >   Foxo4 antibody - C-terminal region   

Foxo4 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Foxo4 antibody - C-terminal region AI11447

    WB Suggested Anti-Foxo4 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Pancreas
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99MK2
Other Accession NM_001005872, NP_001005872
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 54kDa
Additional Information
Gene ID 192218
Alias Symbol Afxh, MGC117660, Mllt7, afx
Other Names Histone acetyltransferase KAT5,, 60 kDa Tat-interactive protein, Tip60, Histone acetyltransferase HTATIP, Lysine acetyltransferase 5, Kat5, Htatip, Tip60, Tip60b
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Foxo4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFoxo4 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Kat5
Synonyms Htatip, Tip60, Tip60b
Function Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. Relieves NR1D2-mediated inhibition of APOC3 expression by acetylating NR1D2. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. Promotes FOXP3 acetylation and positively regulates its transcriptional repressor activity (By similarity).
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q92993}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q92993}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q92993}. Note=Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region. {ECO:0000250|UniProtKB:Q92993}
Research Areas
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$ 293.00
Cat# AI11447
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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