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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   NEUROD2 antibody - C-terminal region   

NEUROD2 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - NEUROD2 antibody - C-terminal region AI11454

    WB Suggested Anti-NEUROD2 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:1562500
    Positive Control: Human cerebellum
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15784
Other Accession NM_006160, NP_006151
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog
Predicted Mouse, Rabbit, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 41kDa
Additional Information
Gene ID 4761
Alias Symbol NDRF, bHLHa1
Other Names Neurogenic differentiation factor 2, NeuroD2, Class A basic helix-loop-helix protein 1, bHLHa1, NeuroD-related factor, NDRF, NEUROD2, BHLHA1, NDRF
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-NEUROD2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsNEUROD2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BHLHA1, NDRF
Function Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections; involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}
Research Areas
Citations (0)

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Westerman,B.A., et al., (2004) Biochim. Biophys. Acta 1676 (1), 96-103Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 293.00
Cat# AI11454
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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