|Application ||WB, IHC|
|Other Accession||NM_001039694, NP_001034783|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Dog|
|Predicted||Mouse, Rat, Pig, Chicken, Bovine, Dog|
|Alias Symbol||FAAR, MGC3931, NR1C2, NUC1, NUCI, NUCII, PPAR-beta, PPARB|
|Other Names||Peroxisome proliferator-activated receptor delta, PPAR-delta, NUCI, Nuclear hormone receptor 1, NUC1, Nuclear receptor subfamily 1 group C member 2, Peroxisome proliferator-activated receptor beta, PPAR-beta, PPARD, NR1C2, PPARB|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-PPARD antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PPARD antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.|
|Tissue Location||Ubiquitous with maximal levels in placenta and skeletal muscle|
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