|Other Accession||NM_015066, NP_055881|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Dog|
|Predicted||Mouse, Rat, Rabbit, Pig, Chicken, Dog|
|Other Names||Tripartite motif-containing protein 35, Hemopoietic lineage switch protein 5, TRIM35, HLS5, KIAA1098|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 100 ul of distilled water. Final anti-TRIM35 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TRIM35 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth (PubMed:25263439). Involved in the cell death mechanism (By similarity).|
|Cellular Location||Cytoplasm. Nucleus. Note=Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Lalonde,J.P., (2004) J. Biol. Chem. 279 (9), 8181-8189Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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