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UTX antibody - middle region

Rabbit Polyclonal Antibody

  • WB - UTX antibody - middle region AI11560

    WB Suggested Anti-UTX Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: MCF7 cell lysate
    KDM6A is strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15550
Other Accession NM_021140, NP_066963
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog
Predicted Human, Zebrafish
Host Rabbit
Clonality Polyclonal
Calculated MW 154kDa
Additional Information
Gene ID 7403
Alias Symbol DKFZp686A03225, MGC141941, bA386N14.2, UTX, KABUK2
Other Names Lysine-specific demethylase 6A, 1.14.11.-, Histone demethylase UTX, Ubiquitously-transcribed TPR protein on the X chromosome, Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein, KDM6A, UTX
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-UTX antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsUTX antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KDM6A
Synonyms UTX
Function Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Cellular Location Nucleus.
Research Areas
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Hong,S., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (47), 18439-18444 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 293.00
Cat# AI11560
(40 western blots)
Availability: 2-3 days
Bulk Size
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