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> home > Products > Primary Antibodies > Antibody Collections > Zebrafish > Prrx1 Antibody - C-terminal region
Prrx1 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P63014 |
| Other Accession | NM_153821, NP_722543 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Pig, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 26kDa |
| Gene ID | 266813 |
|---|---|
| Alias Symbol | Pmx1, Prx-1 |
| Other Names | Paired mesoderm homeobox protein 1, Paired-related homeobox protein 1, PRX-1, rHox, Prrx1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Prrx1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Prrx1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Prrx1 |
|---|---|
| Function | Master transcription factor of stromal fibroblasts for myofibroblastic lineage progression. Orchestrates the functional drift of fibroblasts into myofibroblastic phenotype via TGF-beta signaling by remodeling a super-enhancer landscape. Through this function, plays an essential role in wound healing process. Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer. May play a role in homeostasis and regeneration of bone, white adipose tissue and derm. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:P63013, ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE- ProRule:PRU00138} |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI11577
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